💬 “Evolution doesn't select for longevity. It doesn't care how long you live.” ~Venki Ramakrishnan

⚡️ Venki Ramakrishnan is a Nobel Prize-winning biologist, former president of the Royal Society and author of Why We Die: The New Science of Ageing and Longevity.

⚡ In this episode Venki and I uncover the science of why we die, whether there’s a biological reason why we can’t live forever, and what will happen if we do eventually crack the longevity code.

🎧 Stay tuned to find out:
➡ Whether the $30 billion longevity industry has brought us any closer to immortality
➡︎ Why we’re living longer, but with more disability and disease than ever
➡︎ Why death and our own mortality makes life worth living
➡︎  How even scientists are taking controversial longevity drugs like metformin
➡︎ The best, science-backed ways to add healthy years onto your life

📕 Chapters
0:00 Intro
0:32 Why do we die?
3:06 What do we mean by death?
4:26 Are we close to reversing death?
5:57 Why we want to live forever
9:11 Do humans have an age limit?
11:07 Living healthier for longer
16:06 What causes ageing?
21:15 Your chronological age doesn’t matter
26:17 How to improve biological age
28:16 Why some animals live longer
31:35 Dangers of experimental longevity “hacks”
40:42 Ethical dilemmas of extending lifespan
46:04 Simple ways to life for longer
47:52 Memento Mori
53:46 Longevity research that works

📱 Connect with me:
TikTok: https://www.instagram.com/drkaranrajan
Instagram: https://www.tiktok.com/@dr.karanr
🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

🎙️ An OG Podcasts production.

💬 “If you have a problem with your sleep, it'll worsen just about every medical condition or psychiatric condition that you're experiencing. ~Dr Sujay Kansagra

⚡️ Dr Sujay Kansagra is a double board certified sleep specialist, also known as That Sleep Doc on Instagram. He’s stacked full of solutions on how you can get to sleep faster, feel more rested and deal with issues like insomnia.

⚡ In this episode Sujay and I explain the science of good sleep and share plenty of hacks for you to try out.

🎧 Stay tuned to find out:
➡︎ Why you’re a night owl (or morning lark) - and how to change your chronotype
➡ Whether sleep trackers are worth it (plus Sujay’s alternative recommendation)
➡︎ The science of cognitive shuffling and warm showers for falling asleep faster
➡︎ Why teenagers love a lie in and whether it’s dangerous to ‘sleep train’ a baby
➡︎ Whether women really need 10 hours of sleep

📕 Chapters
0:00 Intro
0:28 How poor sleep = poor health
3:01 The science of sleep
6:02 How to change your chronotype
11:46 Does school need to change so kids can sleep more?
14:09 Benefits of SAD lamps
16:10 How long should you sleep, really?
18:19 Do women really need 10 hours of sleep?
20:59 Are sleep trackers worth it?
29:31 The next big sleep technology
31:58 Keeping a sleep diary
33:07 Can you ever catch up on lost sleep?
36:17 Tricks to get to sleep and cure insomnia
41:02 Does cognitive shuffling work?
42:25 Getting room temperature right
44:34 Is sleep training babies dangerous?

📱 Connect with me:
TikTok: https://www.instagram.com/drkaranrajan
Instagram: https://www.tiktok.com/@dr.karanr

📱 Connect with Sujay
Instagram: https://www.instagram.com/thatsleepdoc/

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

🎙️ An OG Podcasts production.

💬 “Hello, wake up everyone. We are living in the 21st century. We are now able to make you live into your 90s, 100s. But that does mean you will be living with chronic disease. So it is everyone's business.” ~Dr Elena Mucci

⚡️ Dr Elena Mucci is consultant physician, geriatrician and university lecturer. She has a strong presence online and features on many TV shows and podcasts, sharing her expert knowledge of geriatrics.

⚡ In this episode Elena and I destigmatise old age and show why it’s vital that everyone, no matter your age, starts planning for their older years now.

🎧 Stay tuned to find out:
➡︎ What lifestyle factors in your youth impact your risk of age related diseases
➡ How prescription meds are behind 50% of emergency department cases
➡︎ How weight-lifting drastically reduces your chance of dying when you’re older
➡︎ The real danger of alcohol and its link to dementia
➡︎ Why older people are turning more and more to Ozempic

📕 Chapters
0:00 Intro
1:28 What is a  geriatrician really?
4:22 How to fight age related disease when you’re young
7:44 Preparing for old age
13:09 Why we need personalised treatment
18:44 Preventing falls starts in your youth
24:13 What alcohol is really doing to your brain
36:52 Loneliness and mental health
41:43 The dangers of too much prescription meds
47:16 Ozempic in older people

📱 Connect with me:
TikTok: https://www.instagram.com/drkaranrajan
Instagram: https://www.tiktok.com/@dr.karanr

📱 Connect with Elena:
Instagram: https://www.instagram.com/doctor.elenamucci/
Website: https://doctorelenamucci.co.uk/

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

🎙️ An OG Podcasts production.

💬 “We're chronically online, chronically on our phones and tablets. But we need to spend more time outdoors and playing outside and getting our hands in dirt.” ~Dr Zachary Rubin

⚡️ Dr Zachary Rubin is a pediatric allergist and clinical immunologist, known for hula hooping and sporting a variety of colourful bowties on social media.

⚡ In this episode Zach and I go deep into food and pet allergies - what causes them, how to deal with them, and tips on using nasal sprays and other at home remedies. We also delve into the wildfire situation in LA and find out whether human metapneumovirus really is a pandemic level threat.

🎧 Stay tuned to find out:
➡︎ Why we need to get dirty and stop washing our bodies so much
➡︎ Why at-home food sensitivity tests are a scam!
➡ How to deal with pet allergies so you don’t have to let your furry friend go
➡︎ The truth about HMPV and why a bird flu pandemic is the real concern
➡︎ How the LA wildfires are really impacting human health

📕 Chapters
0:00 Intro
2:00 Signs you might have a hidden allergy
5:11 The unusual link between certain allergies
7:54 Why you shouldn’t trust food sensitivity tests
11:38 The dangers of oral food allergy challenges
14:59 Dealing with pet allergies
21:19 How to train your immune system
26:58 The next pandemic threat
34:13 Health impact of LA wildfires
38:58 Highlighting the importance of air quality
43:30 Health risks of neti pots and saline rinses
46:22 Best way to use nasal sprays
51:45 Are nasal strips effective?

📱 Connect with me:
TikTok: https://www.instagram.com/drkaranrajan
Instagram: https://www.tiktok.com/@dr.karanr

📱 Connect with Zach:
YouTube: https://www.youtube.com/@rubin_allergy
Instagram: https://www.instagram.com/rubin_allergy/

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

🎙️ An OG Podcasts production.

💬 “ I would say [weight loss injections] come pretty close to being health elixirs. Taking these drugs is better for almost everyone, than not taking these drugs.” ~Dr Mike Israetel

⚡️ Returning guest Dr Mike Israetel is a fitness expert with a PhD in Sport Physiology. As the founder of Renaissance Periodization, Mike is known for his science-based approach to training and nutrition.

⚡ In this episode Dr Mike and I bring you a New Years resolution special - with a twist. As we discuss the science of setting realistic goals and sticking to them, a surprising conversation around Ozempic and TRT unfolds.

🎧 Stay tuned to find out:
➡︎ How to create habit loops and why goals should be tailored to small consistent wins
➡︎ Why Mike thinks everyone should be taking Ozempic and weight-loss injections
➡ Whether rising beauty stands are really the problem they’re made out to be
➡︎ What’s going on with the rise in TRT use
➡︎ How we have billionaires to thank for testing out the supplements of tomorrow

📕 Chapters
0:00 Intro
1:16 The science of habit building for the New Year
6:07 Making goals as easy as possible
10:57 Using weight loss injections for habit forming
15:24 Are the risks of Ozempic worth it if you’re not overweight?
21:46 Should we fear taking Ozempic for life?
30:30 The casual rise of TRT
39:04 Body dysmorphia and rising beauty standards
44:40 Bryan Johnson and anti-ageing influencers

📱 Connect with me:
TikTok: https://www.instagram.com/drkaranrajan
Instagram: https://www.tiktok.com/@dr.karanr

📱 Connect with Mike:
YouTube: https://www.youtube.com/@RenaissancePeriodization
Instagram: https://www.instagram.com/drmikeisraetel/

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

🎙️ An OG Podcasts production.

We’re all suffering from Brain Rot and we know it. That persistent feeling our brain is slowly turning to mush thanks to our overconsumption of digital junk food.

I’m exactly the same.

At least, I was. But in this video I explain how I’ve been able to take control of my life again over the last couple of years and fight back against Brain Rot. You can do the same too.

Click here to sign up to my newsletter for practical tips on how to improve your health, and the odd dodgy joke, every week: https://www.drkaranrajan.com

Timestamps

0:00 Introduction
2:46 How did we get here?
5:41 How the Internet Changed Everything
9:03 How I fought back against Brain Rot

References

1. Worldwide daily average phone use https://datareportal.com/reports/digital-2024-global-overview-report

2. Sensory specific satiety study https://www.sciencedirect.com/science/article/abs/pii/S0195666384800069


The Joke

And here’s the usual terrible joke:

Why did the skibidi toilet fail its maths test? It couldn’t handle the number two!

💬 “ Eye health, your vision, is so much more than just, ‘I think I see well’. There's way more going on.” ~Dr Joseph Allen

⚡️ Dr Joseph Allen, aka Doctor Eye Health, is an optometrist in the US with a massive following on social media, where he shares science-backed ways to protect your eyes.

⚡️ In this episode Joey and I explain why it’s time to get serious about eye health, as poor eyesight is on the rise globally, bringing many other problems with it.

🎧 Stay tuned to find out:
➡︎ Why half of the world is expected to have myopia (nearsightedness) by 2050
➡︎ How screens are making us blink less (and why that’s bad)
➡ What to do about eyelid twitches, bags and dark circles
➡︎ What foods, diets and supplements work for better vision
➡︎ The best ways to get proactive about your eye health now

📕 Chapters
0:00 Intro
1:00 Dr Allen’s inspiration
3:45 Do glasses make your eyes worse?
8:40 The myopia epidemic
15:06 Lifestyle changes to improve eye health
17:06 Sunlight and eye health
21:53 Are blue light blocking glasses any good?
26:12 Red and orange lights at night
28:03 Best foods for vision - the carrot myth
32:33 Supplements and eye drops
36:35 Intermittent fasting and eye health
39:45 How to deal with dry eyes
46:58 The 20/20/20 rule
49:00 How stress affects the eye
57:00 When should you get checked out?

📱 Connect with me:
TikTok: https://www.instagram.com/drkaranrajan
Instagram: https://www.tiktok.com/@dr.karanr

📱 Connect with Joseph
YouTube: https://www.youtube.com/doctoreyehealth
Instagram: https://www.instagram.com/doctoreyehealth/?hl=en

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

🎙️ An OG Podcasts production.

💬 “ The mouth is the gateway to the entire body. It's not just about having a cute, pretty, cosmetically nice smile. It really directly impacts your overall health in so many ways.” ~Whitney DiFoggio

⚡️ Whitney DiFoggio, AKA TeethTalkGirl, is a dental hygienist who shares evidence-based dental advice online - while debunking all the misinformation out there.

⚡ In this episode Whitney and I discuss the steps you need to take to build the perfect oral hygiene routine, why so many of us are at risk of issues like gum disease and the truth behind all the wild claims flying around.

🎧 Stay tuned to find out:
➡︎ Why you’re only cleaning 60% of your teeth if you skip out on flossing
➡︎ The science of mouthwash, miswak toothbrushes, water flossing & tonsil stones
➡ Why at-home teeth whitening might be making them more yellow
➡︎ Why it’s crazy to skip out on fluoride in your toothpaste
➡︎ The link between oral health and cognitive decline

📕 Chapters
0:00 Intro
1:15 How much should you brush?
6:04 Electric vs manual vs natural toothbrushes
11:36 Benefits of xylitol gum
13:14 What toothpaste is the best?
15:10 The anti-fluoride movement
19:46 Mouthwash is dangerous?
23:33 How oral health is connected to overall health
29:48 How tooth loss leads to cognitive decline
33:04 Flossing, useful or not?
40:17 Should you be tongue scraping?
42:28 The rise of teeth whitening
47:25 How often should you get your teeth checked?
49:02  Whitney's dental routine


📱 Connect with me:
TikTok: https://www.instagram.com/drkaranrajan
Instagram: https://www.tiktok.com/@dr.karanr

📱 Connect with Whitney:
YouTube: https://www.youtube.com/c/TeethTalk/about
Instagram: https://www.instagram.com/teethtalkgirl/

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

🎙️ An OG Podcasts production.

💬 “ I know my patients get nervous around me, because this is not their normal, right? But I am looking at genitalia and examining people every single day, multiple times a day.” ~Dr Rena Malik

⚡️ Dr Rena Malik is a board-certified urologist, pelvic surgeon, sexual health expert and YouTuber. Her channel covers everything from frequent nighttime peeing, to erectile dysfunction, vaginal dryness, orgasms and penis enlargement.

⚡️ In this episode Rena and I are removing the shame and stigma of talking about these issues, so you can feel properly informed, and empowered, to take control of your health - whatever’s going on.

🎧 Stay tuned to find out:
➡︎ The science of your pelvis and how to look after it
➡︎ Just how common erectile dysfunction really is (and what to do about it)
➡ Why penis size really doesn’t matter (and the reality of penis lengthening procedures)
➡︎ Whether masturbation really reduces your risk of getting prostate cancer
➡︎ How to stop incontinence and frequent nighttime urination

📕 Chapters
0:00 Intro
1:25 Most commons issues
2:32 How to deal with embarrassment
5:54 Organs in the pelvis
9:02 Erectile dysfunction
11:31 ED a sign of heart problems?
14:52 Foods to eat for ED
18:01 Why young men are using viagra
21:50 Do you need a bigger penis?
25:21 Penis enlargement, safe or not?
29:17 Prostate health
33:41 Does masturbating lower cancer risk?
37:21 Female pelvic floor health
42:09 Incontinence issues
48:41 Training the pelvic floor muscles

📱 Connect with me:
TikTok: https://www.instagram.com/drkaranrajan
Instagram: https://www.tiktok.com/@dr.karanr

📱 Connect with Rena:
YouTube: https://www.youtube.com/@RenaMalikMD
Instagram: https://www.instagram.com/renamalikmd/

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

🎙️ An OG Podcasts production.

💬 “Anybody can fall prey to this type of misinformation. It does a lot of harm” ~Dr Andrea Love

⚡️ Dr Andrea Love is an immunologist and microbiologist, and founder of ImmunoLogic - an organisation dedicated to debunking the worst of internet pseudoscience and improving science literacy.

⚡️ Andrea and I have a long list of misinformation to get through in this episode. Claims like fluoride lowers your IQ, GMOs are scary and mammograms give you cancer - and that’s not the half of it.

🎧 Stay tuned to find out:
➡︎ How we all have the capacity to fall prey to misinformation - and how to spot it
➡︎ How cancer misinformation can be lethal
➡ The dangers of the raw milk trend
➡︎ What the science really says about fluoride
➡︎ Why organic probably isn’t worth your money

📕 Chapters
0:00 Intro
1:02 Why good information is hard to find
3:36 Coffee and aloe vera gives you cancer?
9:45 Mammograms cancer myth
16:06 The real harm of misinformation
23:14 Do supplements work?
30:34 What does organic actually mean?
34:53 GMO fear
42:31 Fluoride lowers IQ?
49:04 Rise of the raw milk craze

📱 Connect with me:
TikTok: https://www.instagram.com/drkaranrajan
Instagram: https://www.tiktok.com/@dr.karanr

📱 Connect with Andrea:
Instagram: https://www.instagram.com/dr.andrealove/
Website: https://www.immunologic.org/

🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe

🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

🎙️ An OG Podcasts production.